Article
Characterization of monoclonal antibodies specific to the activated ras p21 with aspartic acid at position 13.
Oncogene - 1 Aug 1990
La Vecchio J A, Hamer P J, Ng S C, Trimpe K L, Carney W P
Abstract excerpt
The ras proto-oncogenes encode membrane bound proteins (p21) which are structurally distinct from the proteins encoded by the activated transforming ras genes. These activated ras genes have been identified in various human tumors as well as their preneoplastic lesions such as colorectal tumors (...
Topics
- Animals
- Antibodies, Monoclonal
- Aspartic Acid
- Blotting, Western
- Enzyme-Linked Immunosorbent Assay
- Gene Expression Regulation, Neoplastic
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Mutation
- Precipitin Tests
- Proto-Oncogene Proteins
- Proto-Oncogene Proteins p21(ras)