Article
NK-like T cells and plasma cytokines, but not anti-viral serology, define immune fingerprints of resilience and mild disability in exceptional aging.
PloS one - 1 Jan 2011
Vallejo Abbe N, Hamel David L, Mueller Robert G, Ives Diane G, Michel Joshua J, Boudreau Robert M, Newman Anne B
Abstract excerpt
Exceptional aging has been defined as maintenance of physical and cognitive function beyond the median lifespan despite a history of diseases and/or concurrent subclinical conditions. Since immunity is vital to individual fitness, we examined immunologic fingerprint(s) of highly functional elders. Therefore, survivors of the Cardiovascular Health Study in Pittsburgh, Pennsylvania, USA were recruited (n = 140;...
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