Article
Proinflammatory status influences NK cells subsets in the elderly.
Immunology letters - 1 Nov 2014
Campos Carmen, Pera Alejandra, Lopez-Fernandez Isabel, Alonso Corona, Tarazona Raquel, Solana Rafael
Abstract excerpt
Aging is associated to dysfunctional changes in the immune system, a process termed immunosenescence. Elderly individuals usually present chronic low level inflammation, likely as the consequence of continued exposure to antigens combined with poor immune function, increases in production of pro-inflammatory cytokines by effector memory and senescent T cells and macrophages. This condition not only results from,...
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