Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A genetic variant in the IL-17 promoter is functionally associated with acute graft-versus-host disease after unrelated bone marrow transplantation.

PloS one - 1 Jan 2011

Espinoza J Luis, Takami Akiyoshi, Nakata Katsuya, Onizuka Makoto, Kawase Takakazu, Akiyama Hideki, Miyamura Koichi, Morishima Yasuo, Fukuda Takahiro, Kodera Yoshihisa, Nakao Shinji

Abstract excerpt

Interleukin IL-17 is a proinflammatory cytokine that has been implicated in the pathogenesis of various autoimmune diseases. The single nucleotide polymorphism (SNP), rs2275913, in the promoter region of the IL-17 gene is associated with susceptibility to ulcerative colitis. When we examined the impact of rs2275913 in a cohort consisting of 438 pairs of patients and their unrelated donors transplanted through the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Acute Disease
Share to Bone Marrow Transplantation
Share to Graft vs Host Disease
Share to Infant
Share to Interleukin-17
Share to NFATC Transcription Factors
Share to Promoter Regions, Genetic
Share to Unrelated Donors

Source

Open in PubMed Open full text

Identifiers

PMID: 22028838
DOI: 10.1371/journal.pone.0026229
PMCID: PMC3197629

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A genetic variant in the IL-17 promoter is functionally associated with acute graft-versus-host disease after unrelated bone marrow transplantation.PMID 22028838Read ↗

A single nucleotide polymorphism of IL-17 gene in the recipient is associated with acute GVHD after HLA-matched unrelated BMT.Semantic proximity Read ↗

Association of IL-17 gene polymorphisms and serum level with graft versus host disease after allogeneic hematopoietic stem cell transplantation.Semantic proximity Read ↗

Genetic Analysis of IL-17 Gene Polymorphisms in Gout in a Male Chinese Han Population.Semantic proximity Read ↗

Recipient IL-17A polymorphism rs2275913 is associated with acute graft-versus-host disease after single-unit cord blood transplantation.Semantic proximity Read ↗

Polymorphisms in the IL-17 Gene (rs2275913 and rs763780) Are Associated with Hepatitis B Virus Infection in the Han Chinese Population.Semantic proximity Read ↗

Association of interleukin-17F 7488 single nucleotide polymorphism and inflammatory bowel disease in the Chinese population.Semantic proximity Read ↗

The IL-17 family in diseases: from bench to bedsideSemantic proximity Read ↗

Associations of genotypes and haplotypes of IL-17 with risk of gastric cancer in an eastern Chinese population.Semantic proximity Read ↗

The role of IL-23/IL-17 axis in human kidney allograft rejection.Semantic proximity Read ↗

The IL-17A G-197A and IL-17F 7488T/C polymorphisms are associated with increased risk of cancer in Asians: a meta-analysis.Semantic proximity Read ↗

Frequency distribution of IL-17A G197A (rs2275913) and IL-17F A7488G (rs763780) polymorphisms among healthy Sudanese population.Semantic proximity Read ↗

IL-17A )rs2275913; G197A) gene polymorphism as predictor for disease severity and its correlation with IL-17 serum levels in COVID-19 patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.