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Article

Quantitative detection of single amino acid polymorphisms by targeted proteomics.

Journal of molecular cell biology - 1 Oct 2011

Su Zhi-Duan, Sun Liang, Yu Dan-Xia, Li Rong-Xia, Li Huai-Xing, Yu Zhi-Jie, Sheng Quan-Hu, Lin Xu, Zeng Rong, Wu Jia-Rui

Abstract excerpt

Single-nucleotide polymorphisms (SNPs) are recognized as one kind of major genetic variants in population scale. However, polymorphisms at the proteome level in population scale remain elusive. In the present study, we named amino acid variances derived from SNPs within coding regions as single amino acid polymorphisms (SAPs) at the proteome level, and developed a pipeline of non-targeted and targeted proteomics...

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PMID: 22028381
DOI: 10.1093/jmcb/mjr024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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