Article
Molecular basis for population variation: from SNPs to SAPs.
FEBS letters - 31 Aug 2012
Wu Jia-Rui, Zeng Rong
Abstract excerpt
Single nucleotide polymorphisms (SNPs) are one type of genomic DNA variations in a population. Correspondingly, single amino-acid polymorphisms (SAPs) derived from non-synonymous SNPs represent protein variations in a population. Recently, using proteomic approaches, SAPs in the plasma proteomes of an Asian population were systematically identified for the first time. That study showed that heterozygous and...
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