Article
The c-erb B-2 proto-oncogene in human pancreatic cancer.
The Journal of pathology - 1 Jul 1990
Hall P A, Hughes C M, Staddon S L, Richman P I, Gullick W J, Lemoine N R
Abstract excerpt
The c-erb B-2 oncogene encodes a 190 kD transmembrane growth factor receptor which is closely related to the EGF receptor and has been found to be amplified and overexpressed in a number of human adenocarcinomas, particularly of the breast. We have analysed, by immunocytochemistry using the 21N antibody, expression of c-erb B-2 in a retrospective series of pancreatic adenocarcinoma, chronic pancreatitis, and...
Topics
- Adenocarcinoma
- Base Sequence
- Humans
- Immunoenzyme Techniques
- Molecular Sequence Data
- Mutation
- Nucleic Acid Hybridization
- Pancreatic Neoplasms
- Polymerase Chain Reaction
- Proto-Oncogene Mas
- Proto-Oncogenes