Article
[Pancreatic intraepithelial neoplasia in chronic pancreatitis].
Zentralblatt fur Chirurgie - 1 Nov 2001
Tannapfel A, Witzigmann H, Wittekind C
Abstract excerpt
Chronic pancreatitis causes destruction of the pancreatic gland which leads to tissue fibrosis and regenerative hyperplasia of the epithelium of pancreatic ducts and ductules. Morphological studies revealed distinct proliferative lesions in the pancreatic ducts and ductules adjacent to infiltrating adenocarcinomas of the pancreas. A stepwise progression from mild to severe dysplasia in these hyperplastic lesions...
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