Article
A proteomic view on genome-based signal peptide predictions.
Genome research - 1 Sept 2001
Antelmann H, Tjalsma H, Voigt B, Ohlmeier S, Bron S, van Dijl J M, Hecker M
Abstract excerpt
The availability of complete genome sequences has allowed the prediction of all exported proteins of the corresponding organisms with dedicated algorithms. Even though numerous studies report on genome-based predictions of signal peptides and cell retention signals, they lack a proteomic verification. For example, 180 secretory and 114 lipoprotein signal peptides were predicted recently for the Gram-positive...
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