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Article

Genetic variants of α-synuclein are not associated with essential tremor.

Movement disorders : official journal of the Movement Disorder Society - 1 Dec 2011

Ross Owen A, Conneely Karen N, Wang Tao, Vilarino-Guell Carles, Soto-Ortolaza Alexandra I, Rajput Alex, Wszolek Zbigniew K, Uitti Ryan J, Louis Elan D, Clark Lorraine N, Farrer Matthew J, Testa Claudia M

Abstract excerpt

BACKGROUND: Given the overlap between Parkinson's disease and essential tremor, we examined genetic variants in α-synuclein (SNCA) as risk determinants for essential tremor. METHODS: Samples from 661 essential tremor subjects and 1316 control subjects from 4 participating North American sites were included in this study. Parkinson's disease samples (n = 427) were compared against controls. Twenty variants were...

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Identifiers

PMID: 22025277
DOI: 10.1002/mds.23909
PMCID: PMC3677575

Genes

SNCA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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