Article
TGF-β and stem cell factor regulate cell proliferation in the proximal stem cell niche.
The Prostate - 15 Jun 2012
Salm Sarah, Burger Patricia E, Wilson Elaine Lynette
Abstract excerpt
BACKGROUND: Stem cells are located in specific regulatory environments termed niches, which modulate the survival and proliferation of the cells through a variety of both mitogenic and inhibitory cytokines. In the murine prostate, stem cells are located in the proximal region of prostatic ducts. We examined the regulation of murine prostate cells in the stem cell niche by transforming growth factor beta (TGF-β)...
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