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Article

The Germline Stem Cell Niche Unit in Mammalian Testes

1 Apr 2012

Abstract excerpt

This review addresses current understanding of the germline stem cell niche unit in mammalian testes. Spermatogenesis is a classic model of tissue-specific stem cell function relying on self-renewal and differentiation of spermatogonial stem cells (SSCs). These fate decisions are influenced by a niche microenvironment composed of a growth factor milieu that is provided by several testis somatic support cell...

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PMID: 22535892
DOI: 10.1152/physrev.00025.2011

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