Androgen receptor signalling in prostate: effects of stromal factors on normal and cancer stem cells.

Abstract excerpt

The prostate gland is the most common site for cancer in males within the developed world. Androgens play a vital role in prostate development, maintenance of tissue function and pathogenesis of prostate disease. The androgen receptor signalling pathway facilitates that role in both the epithelial compartment and in the underlying stroma. Stroma is a key mediator of androgenic effects upon the epithelium and can...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Mutation
• Share to Neoplastic Stem Cells
• Share to Prostate