Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of a hypertriglyceridemic transgenic miniature pig model expressing human apolipoprotein CIII.

The FEBS journal - 1 Jan 2012

Wei Jingyuan, Ouyang Hongsheng, Wang Yuhui, Pang Daxin, Cong Nathan X, Wang Tiedong, Leng Bingfeng, Li Dong, Li Xiaoping, Wu Rong, Ding Yu, Gao Fei, Deng Yanhong, Liu Bo, Li Ziyi, Lai Liangxue, Feng Haihua, Liu George, Deng Xuming

Abstract excerpt

Hypertriglyceridemia has recently been considered to be an independent risk factor for coronary heart disease, in which apolipoprotein (Apo)CIII is one of the major contributory factors, as it is strongly correlated with plasma triglyceride levels. Although ApoCIII transgenic mice have been generated as an animal model for the study of hypertriglyceridemia, the features of lipoprotein metabolism in mice differ...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apolipoprotein C-III
Share to Fluorescent Antibody Technique

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hypertriglyceridemia

Share to Immunoenzyme Techniques

Share to Intestinal Mucosa

Share to Intestines

Share to Lipoproteins

Share to Sus scrofa

Source

Identifiers

PMID: 22023023
DOI: 10.1111/j.1742-4658.2011.08401.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of a hypertriglyceridemic transgenic miniature pig model expressing human apolipoprotein CIII.PMID 22023023Read ↗

Targeted disruption of LDLR causes hypercholesterolemia and atherosclerosis in Yucatan miniature pigs.Semantic proximity Read ↗

Familial hypercholesterolemia and atherosclerosis in cloned minipigs created by DNA transposition of a human PCSK9 gain-of-function mutant.Semantic proximity Read ↗

Hypertriglyceridemia as a Result of Human apo <i>CII</i> Gene Expression in Transgenic MiceSemantic proximity Read ↗

CRISPR/Cas9-mediated ApoE-/- and LDLR-/- double gene knockout in pigs elevates serum LDL-C and TC levels.Semantic proximity Read ↗

ABCA1 Promotes the de Novo Biogenesis of Apolipoprotein CIII-Containing HDL Particles in Vivo and Modulates the Severity of Apolipoprotein CIII-Induced HypertriglyceridemiaSemantic proximity Read ↗

Small rodent models of atherosclerosis.Semantic proximity Read ↗

The pig as an animal model for human pathologies: A proteomics perspectiveSemantic proximity Read ↗

Severe hypertriglyceridemia in human APOC1 transgenic mice is caused by apoC-I-induced inhibition of LPL.Semantic proximity Read ↗

High density lipoprotein particle size restriction in apolipoprotein A-I(Milano) transgenic mice.Semantic proximity Read ↗

Deficiency of ASGR1 in pigs recapitulates reduced risk factor for cardiovascular disease in humansSemantic proximity Read ↗

Swine Models of Type 2 Diabetes Mellitus: Insulin Resistance, Glucose Tolerance, and Cardiovascular ComplicationsSemantic proximity Read ↗

Apolipoprotein CI causes hypertriglyceridemia independent of the very-low-density lipoprotein receptor and apolipoprotein CIII in mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.