Article
Genotyping performance assessment of whole genome amplified DNA with respect to multiplexing level of assay and its period of storage.
PloS one - 1 Jan 2011
Ho Daniel W H, Yiu Wai Chi, Yap Maurice K H, Fung Wai Yan, Ng Po Wah, Yip Shea Ping
Abstract excerpt
Whole genome amplification can faithfully amplify genomic DNA (gDNA) with minimal bias and substantial genome coverage. Whole genome amplified DNA (wgaDNA) has been tested to be workable for high-throughput genotyping arrays. However, issues about whether wgaDNA would decrease genotyping performance at increasing multiplexing levels and whether the storage period of wgaDNA would reduce genotyping performance have...
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