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Article

Minor changes in the hemagglutinin of influenza A(H1N1)2009 virus alter its antigenic properties.

PloS one - 1 Jan 2011

Strengell Mari, Ikonen Niina, Ziegler Thedi, Julkunen Ilkka

Abstract excerpt

BACKGROUND: The influenza A(H1N1)2009 virus has been the dominant type of influenza A virus in Finland during the 2009-2010 and 2010-2011 epidemic seasons. We analyzed the antigenic characteristics of several influenza A(H1N1)2009 viruses isolated during the two influenza seasons by analyzing the amino acid sequences of the hemagglutinin (HA), modeling the amino acid changes in the HA structure and measuring...

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Identifiers

PMID: 22022458
DOI: 10.1371/journal.pone.0025848
PMCID: PMC3191144

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