Article
"SNP Snappy": a strategy for fast genome-wide association studies fitting a full mixed model.
Genetics - 1 Jan 2012
Meyer Karin, Tier Bruce
Abstract excerpt
A strategy to reduce computational demands of genome-wide association studies fitting a mixed model is presented. Improvements are achieved by utilizing a large proportion of calculations that remain constant across the multiple analyses for individual markers involved, with estimates obtained without inverting large matrices.
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