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Article

Viral decline over 48h and HCV amino acid mutations are related to efficacy of PEG-IFN/ribavirin.

Hepato-gastroenterology - 1 May 2012

Miyasaka Akio, Kumagai Ichiro, Abe Koichi, Suzuki Kazuyuki

Abstract excerpt

BACKGROUND/AIMS: The relationship between mutations and HCV dynamics has not been fully studied in terms of the efficacy of PEG-IFN/Rib combination treatment. Here we aimed to systematically examine HCV dynamics during PEG-IFN/Rib treatment and evaluate the association between amino acid (aa) substitutions in HCV and efficacy of PEG-IFN/Rib treatment. METHODOLOGY: Patients (n=36) having HCV genotype 1b infection...

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PMID: 22020909
DOI: 10.5754/hge11570

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