Article
Outcome and early viral dynamics with viral mutation in PEG-IFN/RBV therapy for chronic hepatitis in patients with high viral loads of serum HCV RNA genotype 1b.
Intervirology - 1 Jan 2010
Sasase Noriko, Kim Soo Ryang, Kudo Masatoshi, Kim Ke Ih, Taniguchi Miyuki, Imoto Susumu, Mita Keiji, Hayashi Yoshitake, Shoji Ikuo, El-Shamy Ahmed, Hotta Hak
Abstract excerpt
We investigated whether sustained virological response (SVR) and non-SVR by chronic hepatitis C patients to pegylated interferon plus ribavirin (PEG-IFN/RBV) combination therapy are distinguishable by viral factors such as the IFN/RBV resistance-determining region (IRRDR) and by on-treatment fact...
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