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The Emerging Role of Histone Demethylases in Renal Cell Carcinoma

3 May 2017

Abstract excerpt

Renal cell carcinoma (RCC), the most common kidney cancer, is responsible for more than 100,000 deaths per year worldwide. The molecular mechanism of RCC is poorly understood. Many studies have indicated that epigenetic changes such as DNA methylation, noncoding RNAs, and histone modifications are central to the pathogenesis of cancer. Histone demethylases (KDMs) play a central role in histone modifications....

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PMID: 28725537
DOI: 10.15586/jkcvhl.2017.56

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