Article
Genetic polymorphisms of matrix metalloproteinases and their inhibitors in potentially malignant and malignant lesions of the head and neck.
Journal of biomedical science - 15 Feb 2010
Chaudhary Ajay Kumar, Singh Mamta, Bharti Alok C, Asotra Kamlesh, Sundaram Shanthy, Mehrotra Ravi
Abstract excerpt
Matrix metalloproteinases (MMPs) are a family of zinc-dependent proteinases that are capable of cleaving all extra cellular matrix (ECM) substrates. Degradation of matrix is a key event in progression, invasion and metastasis of potentially malignant and malignant lesions of the head and neck. It...
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