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Article

Genetic polymorphisms of matrix metalloproteinases and their inhibitors in potentially malignant and malignant lesions of the head and neck.

Journal of biomedical science - 15 Feb 2010

Chaudhary Ajay Kumar, Singh Mamta, Bharti Alok C, Asotra Kamlesh, Sundaram Shanthy, Mehrotra Ravi

Abstract excerpt

Matrix metalloproteinases (MMPs) are a family of zinc-dependent proteinases that are capable of cleaving all extra cellular matrix (ECM) substrates. Degradation of matrix is a key event in progression, invasion and metastasis of potentially malignant and malignant lesions of the head and neck. It might have an important polymorphic association at the promoter regions of several MMPs such as MMP-1 (-1607 1G/2G),...

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Identifiers

PMID: 20152059
DOI: 10.1186/1423-0127-17-10
PMCID: PMC2846899

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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