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Article

A cellular model for the investigation of Fuchs' endothelial corneal dystrophy.

Experimental eye research - 1 Dec 2011

Kelliher Clare, Chakravarti Shukti, Vij Neeraj, Mazur Steve, Stahl Patrick J, Engler Christoph, Matthaei Mario, Yu S Michael, Jun Albert S

Abstract excerpt

Fuchs' endothelial corneal dystrophy is the most common corneal endotheliopathy, and a leading indication for corneal transplantation in the US. Relatively little is known about its underlying pathology. We created a cellular model of the disease focusing on collagen VIII alpha 2 (COL8A2), a collagen which is normally present in the cornea, but which is found in abnormal amounts and distribution in both early and...

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Identifiers

PMID: 22020132
DOI: 10.1016/j.exer.2011.10.001
PMCID: PMC3225702

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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