Article
Copy number variation at 6q13 functions as a long-range regulator and is associated with pancreatic cancer risk.
Carcinogenesis - 1 Jan 2012
Huang Liming, Yu Dianke, Wu Chen, Zhai Kan, Jiang Guoliang, Cao Guangwen, Wang Chunyou, Liu Yu, Sun Menghong, Li Zhaoshen, Tan Wen, Lin Dongxin
Abstract excerpt
Copy number variations (CNVs) have been recognized to contribute to phenotypic variations and to be associated with susceptibility to certain complex diseases. This study examined the functional significance of CNVR2966.1 at 6q13 and its association with pancreatic cancer susceptibility. The CNVR2966.1 was found to be a 10,379 bp nucleotides deletion/insertion within the uniform boundaries chromosome 6:...
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