Sequence-dependent prediction of recombination hotspots in Saccharomyces cerevisiae.

Abstract excerpt

Meiotic recombination does not occur randomly across the genome, but instead occurs at relatively high frequencies in some genomic regions (hotspots) and relatively low frequencies in others (coldspots). Hotspots and coldspots would shed light on the mechanism of recombination, but the accurate prediction of hot/cold spots is still an open question. In this study, we presented a model to predict hot/cold spots in...

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