Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

microRNAs play critical roles in the survival and recovery of Caenorhabditis elegans from starvation-induced L1 diapause.

Proceedings of the National Academy of Sciences of the United States of America - 1 Nov 2011

Zhang Xiaochang, Zabinsky Rebecca, Teng Yudong, Cui Mingxue, Han Min

Abstract excerpt

Environmental stresses and nutrition availability critically affect animal development. Numerous animal species across multiple phyla enter developmental arrest for long-term survival in unfavorable environments and resume development upon stress removal. Here we show that compromising overall microRNA (miRNA) functions or mutating certain individual miRNAs impairs the long-term survival of nematodes during...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to Caenorhabditis elegans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Division

Share to MicroRNAs

Share to Mutation

Share to Starvation

Source

Open in PubMed Open full text

Identifiers

PMID: 22011579
DOI: 10.1073/pnas.1105982108
PMCID: PMC3207661

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

microRNAs play critical roles in the survival and recovery of Caenorhabditis elegans from starvation-induced L1 diapause.PMID 22011579Read ↗

Alternative somatic and germline gene-regulatory strategies during starvation-induced developmental arrestSemantic proximity Read ↗

Transgenerational Effects of Early Life Starvation on Growth, Reproduction, and Stress Resistance in<i>Caenorhabditis elegans</i>Semantic proximity Read ↗

Developmental plasticity and the response to nutrient stress in Caenorhabditis elegansSemantic proximity Read ↗

Timing requirements for insulin/IGF-1 signaling in C. elegans.Semantic proximity Read ↗

Starvation protects germline stem cells and extends reproductive longevity in C. elegans.Semantic proximity Read ↗

Post-developmental microRNA expression is required for normal physiology, and regulates aging in parallel to insulin/IGF-1 signaling in C. elegans.Semantic proximity Read ↗

Alternative somatic and germline gene-regulatory strategies during starvation-induced developmental arrestSemantic proximity Read ↗

A feedback circuit involving let-7-family miRNAs and DAF-12 integrates environmental signals and developmental timing in Caenorhabditis elegans.Semantic proximity Read ↗

Nutrient sensing pathways regulating adult reproductive diapause in C. elegansSemantic proximity Read ↗

daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans.Semantic proximity Read ↗

Cost-free lifespan extension via optimisation of gene expression in adulthood supports the developmental theory of ageingSemantic proximity Read ↗

Early life starvation and Hedgehog-related signaling activate innate immunity downstream of daf-18/PTEN and lin-35/Rb causing developmental abnormalities in adult C. elegansSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.