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Association between pri-miR-218 polymorphism and risk of hepatocellular carcinoma in a Han Chinese population.

DNA and cell biology - 1 May 2012

Zhang Lu-Shun, Liang Wei-Bo, Gao Lin-Bo, Li Hong-Yu, Li Li-Juan, Chen Peng-Yu, Liu Yun, Chen Tian-Yi, Han Jun-Ge, Wei Yong-Gang, Zhang Lin

Abstract excerpt

MicroRNAs are noncoding RNA molecules of 18-25 nucleotides that regulate gene expression at the post-transcriptional level. The aim of this study was to investigate whether pri-miR-218 rs11134527 A/G polymorphism influences the risk of hepatocellular carcinoma (HCC) or not. pri-miR-218 rs11134527 A/G was genotyped in 302 HCC patients and 513 control subjects using the polymerase chain reaction-restriction...

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PMID: 22011248
DOI: 10.1089/dna.2011.1326

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AFP

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