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Article

The impact of pri-miR-218 rs11134527 on the risk and prognosis of patients with esophageal squamous cell carcinoma.

International journal of clinical and experimental pathology - 1 Jan 2014

Jiang Lin, Wang Chaofu, Sun Canlin, Xu Yumin, Ding Zhongqi, Zhang Xueling, Huang Junxing, Yu Hong

Abstract excerpt

MicroRNA-218 (miR-218) acts as a tumor suppressor in numerous types of cancer by regulation of the expression of target genes. The aim of this study was to investigate whether polymorphisms in miR-218 LAMB3 pathway were associated with the risk and prognosis of esophageal squamous cell carcinoma (ESCC). Pri-mir-218 rs11134527 and LAMB3 rs2566 were genotyped in ESCC patients and 745 controls to assess their...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25337271
PMCID: PMC4203242

Genes

LAMB3

Provenance

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