Article
Association of MicroRNA Polymorphisms With Hepatocellular Carcinoma in an Iranian Population.
Annals of laboratory medicine - 1 Jan 2019
Farokhizadeh Zhaleh, Dehbidi Sahar, Geramizadeh Bita, Yaghobi Ramin, Malekhosseini Seyed Ali, Behmanesh Mehrdad, Sanati Mohammad Hossein, Afshari Afsoon, Moravej Ali, Karimi Mohammad Hossein
Abstract excerpt
BACKGROUND: Single nucleotide polymorphisms (SNPs) can modulate various biological processes by influencing microRNA (miRNA) biogenesis and altering target selection. Common SNPs may alter the processing of miRNA and may be associated with hepatocellular carcinoma (HCC). We investigated the relationship between miR-499A>G, miR-149C>T, miR-196a2T>C, and miR-146aG>C and HCC susceptibility, examining the interaction...
Topics
- Adult
- Alleles
- Carcinoma, Hepatocellular
- Case-Control Studies
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Hepatitis B
- Humans
- Iran
- Liver Neoplasms
- Male