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Article

The effect of ABCB1 genetic variants on chemotherapy response in HIV and cancer treatment.

Pharmacogenomics - 1 Oct 2011

Reed Kerry, Parissenti Amadeo M

Abstract excerpt

Despite their clearly distinct pathophysiologies, HIV and cancer are diseases whose response to chemotherapy treatment varies substantially amongst patients, in particular for those with prior drug exposure. This has been attributed, in part, to elevated expression of the ABCB1 drug transporter in some patients, which results in reduced drug accumulation in target tissues. Many mechanisms have been identified for...

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Identifiers

PMID: 22008050
DOI: 10.2217/pgs.11.84

Genes

ABCB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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