Article
Beta-thalassemia in Turkey.
Hemoglobin - 1 Jan 1990
Oner R, Altay C, Gurgey A, Aksoy M, Kilinç Y, Stoming T A, Reese A L, Kutlar A, Kutlar F, Huisman T H
Abstract excerpt
A review is presented of the various beta-thalassemia alleles observed in nearly 191 patients with beta-thalassemia major and their 182 heterozygous relatives. Determination was by gene amplification and dot-blot hybridization with synthetic probes, specific for 27 different mutations. Eighteen m...
Topics
- Adolescent
- Adult
- Alleles
- Base Sequence
- Child
- Child, Preschool
- DNA Mutational Analysis
- Gene Frequency
- Genes
- Genes, Switch
- Genotype
- Globins
- Hemoglobinopathies
- Hemoglobins, Abnormal
- Humans
- Infant
- Middle Aged
- Molecular Sequence Data