Article
A comprehensive molecular characterization of beta thalassemia in a highly heterogeneous population.
Blood cells, molecules & diseases - 15 Jun 2011
Akhavan-Niaki Haleh, Derakhshandeh-Peykar Poupak, Banihashemi Ali, Mostafazadeh Amrollah, Asghari Beheshteh, Ahmadifard Mohammad-Reza, Azizi Mandana, Youssefi Ali, Elmi Maryam Mitra
Abstract excerpt
In Iran, the prevalence of beta-thalassemia trait is approximately 4-8% in most areas, and in Mazandaran province 10% of the population are carriers. Twenty four beta-globin gene mutations were identified in 1635 persons with beta-thalassemia trait using reverse dot blot and restriction fragment...
Topics
- Female
- Gene Order
- Genetic Heterogeneity
- Genetics, Population
- Haplotypes
- Humans
- Iran
- Mutation
- Prevalence
- beta-Globins
- beta-Thalassemia