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Genetic association between ghrelin polymorphisms and Alzheimer's disease in a Japanese population.

Dementia and geriatric cognitive disorders - 1 Jan 2011

Shibata Nobuto, Ohnuma Tohru, Kuerban Bolati, Komatsu Miwa, Arai Heii

Abstract excerpt

BACKGROUND/AIMS: Ghrelin has been reported to enter the hippocampus and to bind to the neurons of the hippocampal formation. This peptide also affects neuronal glucose uptake and decreases tau hyperphosphorylation. There is increasing evidence suggesting an association between ghrelin and Alzheimer's disease (AD) pathology. The aim of this study was to investigate whether single nucleotide polymorphisms (SNPs) of...

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Identifiers

PMID: 22005651
DOI: 10.1159/000333075

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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