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Article

Therapeutic potential of <i>in utero</i> mesenchymal stem cell (MSCs) transplantation in rat foetuses with spina bifida aperta

18 Oct 2011

Abstract excerpt

Neural tube defects (NTDs) are complex congenital malformations resulting from incomplete neurulation in embryo. Despite surgical repair of the defect, most of the patients who survive with NTDs have a multiple system handicap due to neuron deficiency of the defective spinal cord. In this study, we successfully devised a prenatal surgical approach and transplanted mesenchymal stem cells (MSCs) to foetal rat...

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PMID: 22004004
DOI: 10.1111/j.1582-4934.2011.01470.x

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