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The Amniotic Fluid As a Source of Neural Stem Cells in the Setting of Experimental Neural Tube Defects

7 Sept 2012

Abstract excerpt

We sought to determine whether neural stem cells (NSCs) can be isolated from the amniotic fluid in the setting of neural tube defects (NTDs), as a prerequisite for eventual autologous perinatal therapies. Pregnant Sprague-Dawley dams (n=62) were divided into experimental (n=42) and control (n=20) groups, depending on prenatal exposure to retinoic acid for the induction of fetal NTDs. Animals were killed before...

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PMID: 22957979
DOI: 10.1089/scd.2012.0215

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