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The cumulative amount of serum-free light chain is a strong prognosticator in chronic lymphocytic leukemia

14 Oct 2011

Abstract excerpt

Identification of patients at risk of early disease progression is the mainstay of tailored management in chronic lymphocytic leukemia (CLL). Although application of established biomarkers is limited by intrinsic detection/readout complexities, abnormality of κ and λ serum-free light chain ratio [sFLC (κ/λ)] was proposed as a straightforward prognosticator in CLL. By analyzing 449 therapy-naive patients, we show...

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PMID: 21998207
DOI: 10.1182/blood-2011-04-345587

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