Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Abnormal serum free light chain ratios are associated with poor survival and may reflect biological subgroups in patients with chronic lymphocytic leukaemia.

British journal of haematology - 1 Jan 2009

Pratt Guy, Harding Stephen, Holder Roger, Fegan Chris, Pepper Chris, Oscier David, Gardiner Anne, Bradwell Arthur R, Mead Graham

Abstract excerpt

The measurement of immunoglobulin serum free light chains (sFLC) has prognostic significance in plasma cell dyscrasias but its role in chronic lymphocytic leukaemia (CLL) is unknown. This retrospective study from three UK hospitals analysed sFLC in 181 untreated/pre-treatment CLL patients and 78...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to beta 2-Microglobulin
Share to Immunoglobulin Light Chains

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunoglobulin Variable Region

Share to Kaplan-Meier Estimate

Share to Leukemia, Lymphocytic, Chronic, B-Cell

Share to Prognosis

Share to Survival Rate

Share to ZAP-70 Protein-Tyrosine Kinase

Source

Identifiers

PMID: 19016722
DOI: 10.1111/j.1365-2141.2008.07456.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19016722-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Abnormal serum free light chain ratios are associated with poor survival and may reflect biological subgroups in patients with chronic lymphocytic leukaemia.PMID 19016722Read ↗

Prognostic indices in chronic lymphocytic leukaemia: where do we stand how do we proceed?Semantic proximity Read ↗

The cumulative amount of serum-free light chain is a strong prognosticator in chronic lymphocytic leukemiaSemantic proximity Read ↗

Normal serum protein electrophoresis and mutated IGHV genes detect very slowly evolving chronic lymphocytic leukemia patients.Semantic proximity Read ↗

The clinical significance of NOTCH1 and SF3B1 mutations in the UK LRF CLL4 trialSemantic proximity Read ↗

The morphology of CLL revisited: the clinical significance of prolymphocytes and correlations with prognostic/molecular markers in the LRF CLL4 trial.Semantic proximity Read ↗

Elevated IgM and abnormal free light chain ratio are increased in relatives from high-risk chronic lymphocytic leukemia pedigrees.Semantic proximity Read ↗

Soluble CD138 serum levels are not associated with other poor prognostic markers in patients with B-chronic lymphocytic leukaemia.Semantic proximity Read ↗

Diagnostic features and survival in typical and prolymphocytoid variants of chronic lymphocytic leukemia.Semantic proximity Read ↗

Searching for surrogates for IGHV mutations in chronic lymphocytic leukemia.Semantic proximity Read ↗

Prognostic value of ZAP-70 expression in chronic lymphocytic leukemia as assessed by quantitative polymerase chain reaction and flow cytometry.Semantic proximity Read ↗

Combinations of ZAP-70, CD38 and IGHV mutational status as predictors of time to first treatment in CLL.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.