Article
DBGSA: a novel method of distance-based gene set analysis.
Journal of human genetics - 1 Oct 2012
Li Jin, Wang Limei, Xu Liangde, Zhang Ruijie, Huang Meilin, Wang Ke, Xu Jiankai, Lv Hongchao, Shang Zhenwei, Zhang Mingming, Jiang Yongshuai, Guo Maozu, Li Xia
Abstract excerpt
When compared with single gene functional analysis, gene set analysis (GSA) can extract more information from gene expression profiles. Currently, several gene set methods have been proposed, but most of the methods cannot detect gene sets with a large number of minor-effect genes. Here, we propose a novel distance-based gene set analysis method. The distance between two groups of genes with different phenotypes...
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