Lysyl oxidase G473A polymorphism is associated with increased risk of coronary artery diseases.

doi:10.1089/dna.2011.1261

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Lysyl oxidase G473A polymorphism is associated with increased risk of coronary artery diseases.

DNA and cell biology - 1 Dec 2011

Ma Lan, Song Haihan, Zhang Meiyan, Zhang Daifu

Abstract excerpt

Lysyl oxidase (LOX) plays a crucial role in the maintenance of extracellular matrix stability and could participate in vascular remodeling associated with cardiovascular diseases. A novel polymorphism in the LOX gene, G473A (rs1800449), was identified. The objective of this study was to investigate the association between LOX G473A polymorphism and susceptibility to coronary artery diseases (CADs) in Chinese...

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PMID: 21612403
DOI: 10.1089/dna.2011.1261

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