Article
The effect of lysyl oxidase polymorphism on susceptibility and prognosis of nonsmall cell lung cancer.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Dec 2012
Shi Weiwei, Yang Bo, Li Xiaoyan, Sun Shengjie, Wang Lijie, Jiao Shunchang
Abstract excerpt
Lysyl oxidase (LOX) is a copper-dependent amine oxidase that plays important roles in development and homeostasis of the lungs. The aim of this study was to investigate whether polymorphisms in the LOX gene were associated with susceptibility to nonsmall cell lung cancer (NSCLC). We sequenced the promoter region of LOX gene and tested the previously reported polymorphism 473 G/A in the Han Chinese population. A...
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