Article
Infection with human T-lymphotropic virus types I and II results in alterations of cellular receptors, including the up-modulation of T-cell counterreceptors CD40, CD54, and CD80 (B7-1).
Clinical and diagnostic laboratory immunology - 1 May 1995
Dezzutti C S, Rudolph D L, Lal R B
Abstract excerpt
To examine the phenotypic alterations associated with human T-lymphotropic virus types I and II (HTLV-I and -II) infection, long-term cell lines (n = 12 HTLV-I cell lines; n = 11 HTLV-II cell lines; n = 6 virus-negative cell lines) were analyzed for the cell surface expression of various lineage markers (i.e., myeloid, progenitor, and leukocyte), integrin receptors, and receptor-counterreceptor (R-CR) pairs...
Topics
- Antigens, CD
- Antigens, Differentiation, B-Lymphocyte
- B7-1 Antigen
- Biomarkers
- CD40 Antigens
- Cell Line
- HTLV-I Infections
- HTLV-II Infections
- Humans
- Integrins
- Intercellular Adhesion Molecule-1
