Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

STK39 variation predicts the ambulatory blood pressure response to losartan in hypertensive men.

Hypertension research : official journal of the Japanese Society of Hypertension - 1 Jan 2012

Donner Kati M, Hiltunen Timo P, Hannila-Handelberg Tuula, Suonsyrjä Timo, Kontula Kimmo

Abstract excerpt

Large-scale genome-wide association studies (GWASs) have identified significant associations of common genetic variants with blood pressure (BP) levels. To obtain more evidence for the role of these variants in BP regulation, we studied their association with BP responses to four different antihypertensive drug monotherapies. We selected 19 single-nucleotide variants based on data from five GWASs. The study group...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Antihypertensive Agents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Blood Pressure

Share to Blood Pressure Monitoring, Ambulatory

Share to Hydrochlorothiazide

Share to Hypertension

Share to Losartan

Share to Protein Serine-Threonine Kinases

Source

Identifiers

PMID: 21993215
DOI: 10.1038/hr.2011.166

Genes

STK39

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

STK39 variation predicts the ambulatory blood pressure response to losartan in hypertensive men.PMID 21993215Read ↗

Pharmacogenomics in Hypertension: Where We Stand TodaySemantic proximity Read ↗

Pharmacogenomics of amlodipine and hydrochlorothiazide therapy and the quest for improved control of hypertension: a mini reviewSemantic proximity Read ↗

Association of ATP2B1 and STK39 gene variants with blood pressure levels in patients with essential hypertension.Semantic proximity Read ↗

The effects of genes implicated in cardiovascular disease on blood pressure response to treatment among treatment-naive hypertensive African Americans in the GenHAT study.Semantic proximity Read ↗

Single nucleotide polymorphism (SNP) rs4291 of the angiotensin-converting enzyme (ACE) gene is associated with the response to losartan treatment in hypertensive patients.Semantic proximity Read ↗

Association of the Single Nucleotide Polymorphisms in the Renin-Angiotensin-Aldosterone System with Hypertension in the Uzbek Population.Semantic proximity Read ↗

Pharmacoepigenetics of hypertension: genome-wide methylation analysis of responsiveness to four classes of antihypertensive drugs using a double-blind crossover study designSemantic proximity Read ↗

From the Cover: Whole-genome association study identifies STK39 as a hypertension susceptibility gene.Semantic proximity Read ↗

Pharmacogenetic implications for eight common blood pressure-associated single-nucleotide polymorphisms.Semantic proximity Read ↗

Association between CYP11B2 rs1799998 genetic variant with essential hypertension and antihypertensive response.Semantic proximity Read ↗

STK39 polymorphism is associated with essential hypertension: a systematic review and meta-analysis.Semantic proximity Read ↗

AGTR1 variant rs2638355 is associated with increased salt sensitivity of blood pressure: a female-specific effect in individuals from the HyperPath cohort.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.