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Article

Somatic mutations in the transcriptional corepressor gene BCORL1 in adult acute myelogenous leukemia.

Blood - 24 Nov 2011

Li Meng, Collins Roxane, Jiao Yuchen, Ouillette Peter, Bixby Dale, Erba Harry, Vogelstein Bert, Kinzler Kenneth W, Papadopoulos Nickolas, Malek Sami N

Abstract excerpt

To further our understanding of the genetic basis of acute myelogenous leukemia (AML), we determined the coding exon sequences of ∼ 18 000 protein-encoding genes in 8 patients with secondary AML. Here we report the discovery of novel somatic mutations in the transcriptional corepressor gene BCORL1 that is located on the X-chromosome. Analysis of BCORL1 in an unselected cohort of 173 AML patients identified a...

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Identifiers

PMID: 21989985
DOI: 10.1182/blood-2011-05-356204
PMCID: PMC3228503

Genes

BCORL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Somatic mutations in the transcriptional corepressor gene BCORL1 in adult acute myelogenous leukemia.PMID 21989985Read ↗

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