Article
Emergence of myeloid stem cell line from T-lymphoid blastic phase of chronic myeloid leukemia in culture.
Leukemia research - 1 Jan 1992
Mohamed A N, Smith M R, al-Katib A, Wolman S R
Abstract excerpt
A new cell line designated JA-CML was derived from the peripheral blood of a patient with blastic phase CML. Sequential evolution of phenotypic and genetic markers was demonstrated during adaptation from primary to continuous culture in vitro. In the primary sample the majority of blast cells displayed the early T-cell markers, CD7, HLA-DR, and TdT, but were negative for the common ALL antigen (CALLA), CD4 and...
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