Emergence of myeloid stem cell line from T-lymphoid blastic phase of chronic myeloid leukemia in culture.

doi:10.1016/0145-2126(92)90179-b

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Article

Emergence of myeloid stem cell line from T-lymphoid blastic phase of chronic myeloid leukemia in culture.

Leukemia research - 1 Jan 1992

Mohamed A N, Smith M R, al-Katib A, Wolman S R

Abstract excerpt

A new cell line designated JA-CML was derived from the peripheral blood of a patient with blastic phase CML. Sequential evolution of phenotypic and genetic markers was demonstrated during adaptation from primary to continuous culture in vitro. In the primary sample the majority of blast cells dis...

Topics

Antigens, CD
Chromosome Aberrations
Gene Rearrangement
Humans
Karyotyping
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Male
Middle Aged
Phenotype
Tumor Cells, Cultured

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