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Article

Axonopathy Is Associated with Complex Axonal Transport Defects in a Model of Multiple Sclerosis

11 Oct 2011

Abstract excerpt

Multiple sclerosis (MS) is an inflammatory and neurodegenerative disease characterized by myelin and axonal pathology. In a viral model of MS, we tested whether axonopathy initiation and development are based on an impaired transport of neurofilaments. Spinal cords of Theiler's murine encephalomyelitis virus (TMEV)-infected and mock-infected mice and TMEV infected neuroblastoma N1E-115 cells were analyzed by...

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PMID: 21988534
DOI: 10.1111/j.1750-3639.2011.00541.x

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