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Dysregulation of axonal transport and motorneuron diseases

13 Jan 2011

Abstract excerpt

MNDs (motorneuron diseases) are neurodegenerative disorders in which motorneurons located in the motor cortex, in the brainstem and in the spinal cord are affected. These diseases in their inherited or sporadic forms are mainly characterized by motor dysfunctions, occasionally associated with cognitive and behavioural alterations. Although these diseases show high variability in onset, progression and clinical...

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PMID: 21250942
DOI: 10.1042/bc20100093

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