Article
KCNE5 polymorphism rs697829 is associated with QT interval and survival in acute coronary syndromes patients.
Journal of cardiovascular electrophysiology - 1 Mar 2012
Palmer Barry R, Frampton C M, Skelton Lorraine, Yandle Tim G, Doughty Rob N, Whalley Gillian A, Ellis Chris J, Troughton Richard W, Richards A M, Cameron Vicky A
Abstract excerpt
INTRODUCTION: The KCNE family is a group of small transmembrane channel proteins involved in potassium ion (K(+)) conductance. The X-linked KCNE5 gene encodes a regulator of the K(+) current mediated by the potassium channel KCNQ1. Polymorphisms in KCNE5 have been associated with altered cardiac electrophysiological properties in human studies. We investigated associations of the common rs697829 polymorphism...
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