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Article

Cloning, nucleotide sequence, and regulation of the Bacillus subtilis nadB gene and a nifS-like gene, both of which are essential for NAD biosynthesis.

Journal of bacteriology - 1 Mar 1993

Sun D, Setlow P

Abstract excerpt

A number of Bacillus subtilis genes involved in NAD biosynthesis have been cloned and sequenced. One of the genes encodes a polypeptide homologous to Escherichia coli L-aspartate oxidase, and its mutation resulted in a nicotinic acid (Nic)-dependent phenotype; this gene was termed nadB. A second open reading frame (orf2) was found downstream of nadB, and an insertional plasmid separating orf2 and nadB also gave a...

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Identifiers

PMID: 8444804
DOI: 10.1128/jb.175.5.1423-1432.1993
PMCID: PMC193229

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Source receipt: pubmed, retrieved 7 Sept 2026.

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