Cloning, nucleotide sequence, and regulation of the Bacillus subtilis nadB gene and a nifS-like gene, both of which are essential for NAD biosynthesis.

doi:10.1128/jb.175.5.1423-1432.1993

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Article

Cloning, nucleotide sequence, and regulation of the Bacillus subtilis nadB gene and a nifS-like gene, both of which are essential for NAD biosynthesis.

Journal of bacteriology - 1 Mar 1993

Sun D, Setlow P

Abstract excerpt

A number of Bacillus subtilis genes involved in NAD biosynthesis have been cloned and sequenced. One of the genes encodes a polypeptide homologous to Escherichia coli L-aspartate oxidase, and its mutation resulted in a nicotinic acid (Nic)-dependent phenotype; this gene was termed nadB. A second...

Topics

Amino Acid Oxidoreductases
Amino Acid Sequence
Bacillus subtilis
Bacterial Proteins
Base Sequence
Cloning, Molecular
DNA, Bacterial
Escherichia coli Proteins
Gene Expression Regulation, Bacterial
Genes, Bacterial
Kinetics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

NAD

Nicotinamide Mononucleotide

Nitrogen Fixation

Restriction Mapping

Sequence Homology, Amino Acid

Source

Open in PubMed Open full text

Identifiers

PMID: 8444804
DOI: 10.1128/jb.175.5.1423-1432.1993
PMCID: PMC193229

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8444804-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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