Article
A genetic characterization of the nadC gene of Salmonella typhimurium.
Genetics - 1 Apr 1991
Hughes K T, Roth J R, Olivera B M
Abstract excerpt
The nadC gene of Salmonella encodes the pyridine biosynthetic enzyme PRPP-quinolinate phosphoribosyltransferase. Using a combination of genetic techniques, a deletion map for the Salmonella nadC gene has been generated which includes over 100 point mutants and 18 deletion intervals. The nadC alleles obtained by hydroxylamine mutagenesis include those suppressed by either amber, ochre, or UGA nonsense suppressors...
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