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HNF1B polymorphism associated with development of prostate cancer in Korean patients.

Urology - 1 Oct 2011

Kim Hae Jong, Bae Joon Seol, Lee Jaehyouk, Chang In Ho, Kim Kyung Do, Shin Hyoung Doo, Han June Hyun, Lee Shin Young, Kim Wonyong, Myung Soon Chul

Abstract excerpt

OBJECTIVE: To identify whether the genetic variations in HNF1B are associated with the development of prostate cancer in Korean patients. Genome-wide association studies have found the HNF1B gene at 17q12 to be a major causal gene for the risk of prostate cancer. METHODS: We evaluated the association of 47 single nucleotide polymorphisms (SNPs) in the HNF1B gene with prostate cancer risk and clinical...

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PMID: 21982019
DOI: 10.1016/j.urology.2011.06.045

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