Article
Polymorphisms in NFKB1 and NFKBIA Genes Modulate the Risk of Developing Prostate Cancer among Han Chinese.
Medical science monitor : international medical journal of experimental and clinical research - 12 Jun 2015
Han Xiao, Zhang Jia-Jun, Yao Nan, Wang Gang, Mei Juan, Li Bo, Li Chao, Wang Zi-An
Abstract excerpt
BACKGROUND: Nuclear factor kappa B (NF-κB) pathway proteins play an important role in modulating inflammation and other carcinogenic processes. Polymorphisms within NF-κB pathway genes may influence cancer risk. This study aimed to examine the association between NFKB19-4 ATTG ins→del, NFKBIA 3' UTR A→G, -826CT and -881AG polymorphisms and prostate cancer risk among Chinese. MATERIAL AND METHODS: The...
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